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The pharmacokinetics of isotretinoin were evaluated after single and multiple doses in 38 pediatric patients 12 to 15 years and 19 adult patients 18 years who received accutane isotretinoin for the treatment of severe recalcitrant nodular acne.

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Th acn it tats consists o noduls with a diamt o 5 mm o gat. Having this typ o acn can b socially dbilitating, so th potntial o a cu can b li-changing.

This mdicin should b usd with caution in tnags, spcially thos with bon poblms o disass.

Sto th mdicin in a closd contain at oom tmpatu, away om hat, moistu, and dict light. Kp om zing.

It is vy impotant that you docto chck th pogss o you o you child at gula visits to mak su this mdicin is woking poply. Blood tsts may b ndd to chck o unwantd cts.

Taking isottinoin duing pgnancy can caus miscaiag, dath o th tus, o pmatu bith. It can also lad to sv bith dcts such as:

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