A different therapy is recommended if the treated lesion s shows insufficient response to aldara.

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Not commndd oal, ophtalmic, uthal, intavaginal, cvical, ctal, inta-anal human papilloma vial disas.

Mild skin iitation, itching, dynss, laking, scabbing, custing, dnss, hadning th skin wh th mdicin was applid;

A two-ya mous cacinognicity study by dmal administation on th days a wk did not induc tumous at th application sit. Howv, th incidncs hpatocllula tumous among tatd animals w gat than thos contols. Th mchanism this is not known, but as imiquimod has low systmic absoption om human skin, and is not mutagnic, any isk thumans om systmic xposu is likly tb low. uthmo, tumous w not sn at any sit in a 2-ya oal cacinognicity study in ats.

Spons th tatd tumou timiquimod cam should b assssd 12 wks at th nd tatmnt. I th tatd tumou shows an incomplt spons, a dint thapy should b usd (s sction 4.4).

Intns local skin actions including skin wping osion may occu at w applications; may qui intuption dosing.

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new sk lesions may develop during treatment with aldara cream.